By Ahindra Nag
"This state-of-the-art quantity stories the most recent breakthroughs in CADD (Computer-Aided Drug Design), drug supply structures, and permitting technologies"--Provided by means of publisher.
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Communicating with the people and institutions engaged in biologic research and applications. Such communications include e-mail, file transfers, remote logins, electronic bulletin boards, and so on. 3. Organizing, accessing, searching, and the retrieving biologic information, documents, and literature. 4. 6–8 The following thrust areas of biotechnology are fully dependent on bioinformatics: Genomics. The genomics studies in bioinformatics have concentrated on model organisms and the analysis of regulatory systems.
The IDDS reduces or causes no new problems or concerns. 9. Reliability. 10. Marketplace value. The IDDS offers high value by featuring maximum functionality at minimum complexity and cost. Advantages 1. Avoidance of presystemic metabolism 2. Reduction of intra- and interpatient variability 3. Maintenance of drug level in the systemic circulation within the therapeutic window 4. Extension of drug duration of action by a single administration thereby reducing the frequency of dosing Drug Delivery Systems 5.
1â•… Aqueous Solubility and pKa Aqueous solubility of a drug influences its dissolution rate and hence the absorptive power of the drug. Since most drugs are either weak acids or weak bases, pKa is also an important parameter in drug absorption. The pH of the gastric or intestinal fluid and the pH of the blood are indicative of the driving force for absorption based on pH gradient. 3â•… Drug Stability Generally, a drug in the solid state undergoes degradation at a much slower rate than a drug in solution or suspension.