Download Bioinspired Approaches for Human-Centric Technologies by Roberto Cingolani PDF

By Roberto Cingolani

The current publication discusses issues relating to study and improvement of fabrics and units at nanoscale measurement and their respective software in medication and biomedicine.

The person chapters supply an in depth cutting-edge evaluation to the designated subject. it sounds as if disconnected fields - lifestyles sciences, biomedicine, chemistry, physics, drugs and engineering - may be bridged with a hugely interdisciplinary view onto each one subject.

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013 Hou Y et al (2013) NaGdF4 nanoparticle-based molecular probes for magnetic resonance imaging of intraperitoneal tumor xenografts in vivo. ACS Nano 7:330–338. 1021/nn304837c Huang XH, El-Sayed IH, Qian W, El-Sayed MA (2006) Cancer cell imaging and photothermal therapy in the near-infrared region by using gold nanorods. J Am Chem Soc 128:2115–2120. 1021/ja057254a Hudson PJ, Souriau C (2003) Engineered antibodies. Nat Med 9:129–134. 1038/nm0103129 Jain TK, Reddy MK, Morales MA, Leslie-Pelecky DL, Labhasetwar V (2008) Biodistribution, clearance, and biocompatibility of iron oxide magnetic nanoparticles in rats.

Thus, it could help to reconstruct the localization and the volume of the tumor mass with higher precision, reducing costs and time of the diagnosis. To this aim, the group of Chen developed FePt nanoparticles conjugated to anti-HER2 antibody (Chou et al. 2010). Since Pt has a high X-ray absorption coefficient, these nanoparticles were explored as dual imaging probes. The nanoparticles were injected in the tail vein of mice bearing transplanted bladder tumor. MRI and CT imaging of the tumor region were performed before and 24 h after NP injection showing a considerable enhancement of the contrast at tumor site for both imaging techniques and with enhanced contrast in both techniques for the targeted nanoprobes (Chou et al.

ACS Nano 7:7227–7240. 1021/nn4030898 Lu AH, Salabas EL, Schuth F (2007) Magnetic nanoparticles: synthesis, protection, functionalization, and application. Angew Chem Int Ed 46:1222–1244. 200602866 Mader HS, Kele P, Saleh SM, Wolfbeis OS (2010) Upconverting luminescent nanoparticles for use in bioconjugation and bioimaging. Curr Opin Chem Biol 14:582–596. cbpa. 014 Maynard J, Georgiou G (2000) Antibody engineering. Annu Rev Biomed Eng 2:339–376. 339 Mazzucchelli S et al (2010) Single-domain protein a-engineered magnetic nanoparticles: toward a universal strategy to site-specific labeling of antibodies for targeted detection of tumor cells.

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